Research: How spontaneous charging influences the motion of drops on a tilted surface

courtesy of DataPhysics

In April 2022, authors Xiaomei Li, from the Max Planck Institute for Polymer Research in Mainz, Germany, et al. have published an article with the title Spontaneous charging affects the motion of sliding drops in Nature Physics. They have found that the drop motion on a tilted surface is not only determined by viscous dissipation and activated processes, but also by electrostatic forces. We are proud that one of our contact angle meters of the OCA series was used in the experiments conducted for this study. The entire publication can be read on the journal's website.

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DataPhysics releases dpiMAX for its OCA-series

courtesy of DataPhysics

dpiMAX DataPhysics Instruments has developed a new, innovative software for the contact angle meters of its OCA-series: dpiMAX. The software dpiMAX guides the operator, step by step, through the entire workflow and can therefore be operated intuitively. In addition, dpiMAX impresses with a well-organised user interface, which facilitates focused work. Furthermore, several smart functions make measuring especially easy and convenient.

 

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Prof. Daryl Williams Discusses Surface Heterogeneity

snapshotcourtesy of Surface Measurement Systems

In our latest webinar for iGC-SEA week, Prof. Daryl Williams discusses a question he gets a lot, "Are the materials I am testing homogeneous?" 
Surprisingly, most pharmaceutical materials are not homogeneous! 
If you're interested, listen to more on this topic with the link below or watch the full webinar

Watch the full webinar here:

 

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PAMAS AS3 - automated particle counter for liquids

written by Albrecht Truter

The Pamas AS3 is a rather unique system as it is a fully automated particle counting instrument that can measure up to 600
samples per day unattended.It takes automation of particle counting to the next level. The idea of an particle counter connected
to a XY liquid sampler seems routine, but Pamas takes the idea to a whole new level with their many years of experience 
manufacturing  particle counters.

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Study of Single Use Device Performance After 4-Hour Continuous Sampling

BioCapt Single Use microbial impactorcourtesty of Particle Measuring Systems

Also, see this Webinar presented by the authors of this paper.

Abstract

Particle Measuring Systems performed a test to evaluate the BioCapt® Single-Use’s (BCSU’s) ability to recover microorganisms in stressed conditions after four hours of continuous air sampling at 28 LPM. The European Pharmacopoeia Growth Promotion Test performed on the BCSU after incubation shows a good recovery rate (≥ 70%), comparable between the two impactors tested (stressed and unstressed). All three test results aligned with acceptance criteria, and visual inspection of the media post-sampling was satisfactory. This study supports the use of BCSU for four-hour sampling with no change to its monitoring capabilities.

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Pamas S50P Fuel

+courtesy of Pamas 

PAMAS S50P FuelThe online particle counter PAMAS S50P Fuel is used asa online measuring instrument for condition monitoring and contamination analysis of liquid fuel(e.g. diesel). The instrument measures the number of particles in eight different size channels and can function as early alerts in case of failures caused by bigger particle sizes (e.g. corrosion). This makes PAMAS S50P Fuel indispensable for preventive condition monitoring of liquid fuel, as it prevents the filling of contaminated fuel into storage tanks. On its 6-digit LED display, the instrument reports the triple code according to ISO 4406. The PAMAS S50P Fuel is equipped with a pump to control the flow rate to 25 ml/min at a pressure range from 0 to 6 bar.

 

 

 

 

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Product Spotlight :DVS Resolution from Surface Measurment Systems

courtesy of Surface Measurment Systems

DVS ResolutionDVS Resolution is a dual vapor gravimetric analyzer, with key feature, is the combined ability to
precisely control and measure temperature and relative humidity while recording the highest
resolution changes in mass. DVS Resolution uses a dry carrier gas typically nitrogen or
compressed air for its operation.

 

 

 

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Data Trending Requirements Annex 1, Rev 12

Written by Daniele Pandolfi

Data Trending and Alert/Action Levels definition are new requirements in the latest EU GMP Annex 1, Revision 12 draft. Trends allow you to quickly and easily identify changes in your cleanroom data and leverage this to make effective decisions, changes, and adjustments often before problems occur. Here we discuss three key components in the latest Annex 1 draft:

1. Trending Relevance: Current Annex 1 vs rev. 12 draft

2. Environmental Trends: approaches and procedures

3. Alert Level Settings: definition and processes

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FAQ’s: Non viable particle recovery verification after a power outage

Question: “What is the need of taking a non-viable particle count after a power shut down for an hour. Our Class C area is stabilizing
after 30 minutes of a power cut?”

There are several reasons for deploying your Non-Viable Environmental Monitoring Program following a power outage,
but primarily it is to ensure that the HVAC has been restored and is now operating optimally – this is the 30-minute
stabilization that you witness in your Grade C areas. Grade C areas have a relatively high air exchange rate
(nominally, 20 air volumes per hour) so stabilization will occur rapidly in the unmanned state.

  

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Online Workshop: Advanced Methods for Determining Physicochemical Properties of Solid State Materials

courtesy of Surface Measurment Systems

Join us for this workshop organized with the CARPOR platform of the University of Liège to explore pharmaceuticals
and inorganic materials using vapor sorption techniques.

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Why measure particles in fuel and hydraulic fluids

by Albrecht Truter

S40 and SBSSAn liquid particle counter measures the number and size of the particles in a liquid, but why bother to do that ?
This short article will answer that question.

In the case of hydraulic fluids the hydraulic compents has fine tollerances which can be damaged by to
many particles in the fluid.When maintenance are completed it also best practise to flush the system with clean hyraulic fluid and check the fluid is clean after the flush before placing the system back into service. Trend monitoring of hydraulic fluids also serve as an early warning of abnormal wear and possible impending failure in a system.

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The Data Quality Concept – A New Challenge for Quality Experts

courtesy of Particle Measuring Systems

The role of quality systems in pharmaceutical organizations has grown faster than any other function during the last 15 years. During this period, a small group dedicated to traditional Compliance grew and expanded to include Quality Experts in areas such as validation, product release, operations, sterility assurance, and other specialized functions.

Creating a deeper quality connection between manufacturing and engineering has always been the aim of that growth. Little by little, quality became fundamental to every step of the pharmaceutical manufacturing process: changing from a silo concept to a more fluid one. Now, a new challenge is approaching. The fourth industrial revolution (Pharma 4.0™) is the beginning of the “Smart Facility” era, where digitalization and automation will combine to reach very complex applications and life cycles. In this brand-new framework, Quality Experts will face the challenge of rethinking their roles and redesigning the Quality Systems of their pharmaceutical companies to be based on the concepts of Data Quality.

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Just Added – Educational Podcasts from PMS

courtesy of Particle Measuring Systems

What’s new and interesting in the world of environmental monitoring? The 5 most recent podcasts from PMS are listed here. See below for the complete library of archived episodes. Here is the link

How structured surfaces can influence the dewetting behaviour of water droplets during icing and melting cycles

courtesy of Dataphysics

In January 2022, authors Lizhong Wang et al. published an article in Nature Communications with the title Spontaneous dewetting transitions of droplets during icing and melting cycle. In it, they describe how the structure of a surface can influence the behaviour of a droplet during freezing and melting.

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A case study of 4 hours active sampling using the Biocapt Single use - by Particle Measuring Systems

courtesy of Particle Measuring Systems

Extended active microbial sampling is allways of interest due to the possibility
to decrease the number of samples that has to be processed as well as potential
cost savings. Particle Measuring Systems recently released a nice case study
that proves that 4 hours of active sampling is possible.

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